Blood Toluene and Genotoxicity in Gasoline Station Workers in Bangkok: a Preliminary Study
نویسندگان
چکیده
Toluene is widely used as an industrial solvent and is usually produced in the processes of making gasoline. Inhaled toluene may cause genotoxicity and other adverse health effects. This study aimed to ascertain the relation between blood toluene exposure and genotoxicity, as measured by sister chromatid exchange (SCE), by comparing gasoline station workers to controls. Mean blood toluene and SCEs in gas station workers were 225.06 mg/L and 13.62 SCEs/cell, respectively which they were significantly higher than those in controls (p=0.001 and p<0.001, respectively). Also, linear regression analysis showed a significant positive relation (p<0.01) between blood toluene and SCEs. Age was inversely related to SCEs (p<0.01). In conclusion, SCEs may be supported the warning of genotoxicity by toluene exposure in gasoline station workers.
منابع مشابه
Occupational exposure of gasoline station workers to BTEX compounds in Bangkok, Thailand.
BACKGROUND Gasoline station workers are exposed to volatile organic compounds such as benzene, toluene, ethylbenzene and xylene (BTEX). OBJECTIVE To determine the level of exposure to BTEX compounds among gasoline station workers and measure the roadside concentrations of these compounds in the inner and outer areas of Bangkok, Thailand. METHODS 49 workers at 6 gasoline stations in the inne...
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